This Forum examines the unique cancer risks facing Latino men, exploring how cultural norms, environmental exposures, occupational hazards, and emerging science intersect to create a growing—and often overlooked—public health crisis. Experts unpack the influence of machismo on health behaviors, rising rates of testicular and gastric cancers, genetic drivers of colorectal cancer (56% diagnosed at late stage), childhood leukemia disparities, and the disproportionate cancer burdens linked to toxic work environments and climate change. The session highlights the “triple threat” of obesity-diabetes-cancer, actionable strategies for community engagement, and the promise and pitfalls of artificial intelligence in precision oncology and health decision-making.

Key Topics Include:

• How masculinity norms shape men’s cancer risks and care-seeking
• Toxic jobs, climate stressors, and disproportionate exposures for Latino workers
• Genetic and metabolic drivers of colorectal, gastric, and testicular cancers
• Leukemia disparities among Latino children
• Using AI safely and effectively for health information and cancer prevention

Speakers include Luis Arturo Valdez, PhD, MPH (Ganas Health Initiative), Lisa Goldman Rosas, PhD, MPH (Stanford Cancer Institute), Luis Carvajal-Carmona, PhD (UC Davis), María Constanza Camargo, PhD, MS, MHA (NIH/NCI), Enrique Velazquez-Villarreal, MD, PhD, MPH, MS (City of Hope), Leticia Nogueira, PhD, MPH (American Cancer Society), Catherine Metayer, MD, PhD (UC Berkeley), and Katherine A. McGlynn, PhD, MPH (NIH/NCI).