A new community-based pickleball program called Project Rally is helping cancer survivors improve their physical and social well-being, according to a recent pilot study. The program has shown strong results in terms of participation, enjoyment, and physical improvements.

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other drugs.

Researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the disease.

Scientists have created genetically-engineered mice that could help accelerate anti-aging research.

Liposuction and plastic surgery aren't often mentioned in the same breath as cancer. But they are the inspiration for a new approach to treating cancer that uses engineered fat cells to deprive tumors of nutrition. Researchers at UC San Francisco used the gene editing technology CRISPR to turn ordinary white fat cells into 'beige' fat cells, which voraciously consume calories to make heat.

Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice. The novel drug CT-179 was shown to target a specific subset of tumor cells responsible for recurrence and therapy resistance in pediatric brain cancer. The findings could lead to more effective, less toxic treatments, improving survival and quality of life for young patients.

A research team has identified a critical event driving tumor growth in a type of medulloblastoma -- and a way to block it.

For decades, scientists have tried to stop cancer by disabling the mutated proteins that are found in tumors. But many cancers manage to overcome this and continue growing. Now, scientists think they can throw a wrench into the fabrication of a key growth-related protein, MYC, that escalates wildly in 70% of all cancers. Unlike some other targets of cancer therapies, MYC can be dangerous simply due to its abundance.

It's a little pill with big responsibilities. But despite its primary role to prevent pregnancy, the contraceptive pill (or 'the Pill') could also help reduce the risk of ovarian cancer, according to new research.

Researchers have developed a computer model to help scientists identify tumor-fighting immune cells in patients with lung cancer treated with immune checkpoint inhibitors.

A national study seeking more effective treatment for deadly metaplastic breast cancer has identified two inhibitor drugs with the potential to interrupt disease progression.

Psoriasis is a chronic skin disease that manifests itself mainly with skin symptoms (dryness, itching, scaly skin, abnormal patches and plaques). It affects about 2% of the population and is mediated by an altered immune system response that triggers the proliferation of skin cells. Depending on the severity, there are different therapeutic options (topical medications, phototherapy, systemic drugs, etc.), but some conventional treatments can have harmful effects on patients.

The incidence of advanced prostate cancer in California rose markedly in the decade since doctors stopped routinely screening all men for the disease, according to a new study.

Men undergoing radiation therapy for prostate cancer who experience side effects early in treatment may face a higher risk of developing more serious long-term urinary and bowel health issues, according to a new study.

Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to function effectively. Researchers have identified a rare type of immune cells, called stem-like T cells, that holds the key to maintaining powerful, long-term immune responses.

Biomedical engineers have developed an AI-based platform that designs short proteins, termed peptides, capable of binding and destroying previously undruggable disease-causing proteins. Inspired by OpenAI's image generation model, their new algorithm can rapidly prioritize peptides for experimental testing.

A mathematical modeling study suggests that ovarian cancer incidence could be reduced and healthcare savings boosted if women who have already completed their families were offered fallopian tube removal during any other suitable abdominal surgeries.

Cancer symptoms can sometimes be misdiagnosed as normal pregnancy-related changes for women who are expecting, in some cases leading to a delay in treatment, according to a new study.

Personalized medicine aims to tailor treatments to individual patients. Until now, this has been done using a small number of parameters to predict the course of a disease. However, these few parameters are often not enough to understand the complexity of diseases such as cancer. A team of researchers has developed a new approach to this problem using artificial intelligence (AI).

A new study shows that artificial intelligence (AI) can help doctors make better decisions when treating cancer. However, it also highlights challenges in how doctors and AI work together. The study focused on AI-assisted radiotherapy for non-small cell lung cancer and hepatocellular carcinoma (liver cancer).

A new study shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed. The study suggests that doctors may need to rethink current screening guidelines for detecting brain metastasis in patients without symptoms.

The inherited mutated gene WNT9B, which functions normally in embryonic prostate development, increases risk of adult prostate cancer, according to a new study.

Researchers are able to test in parallel the effects of over 1500 active substances on cell metabolism. Their analysis also led to the discovery of previously unknown mechanisms for known medications. This approach might help scientists to better predict side effects and find additional uses for commercially available pharmaceuticals.

A data analysis from a randomized clinical trial for stage 3 colon cancer patients found that patients with evidence of residual cancer in their blood after surgery to remove the cancer, may benefit from adding of celecoxib, to post surgery treatment.

A team of researchers has developed a novel method to enhance the precision of cancer treatment using gold nanoparticles tagged with DNA barcodes.

The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been reviewed.

Researchers propose a novel system that uses standing surface acoustic waves to separate circulating tumor cells from red blood cells with unprecedented precision and efficiency. The platform integrates advanced computational modeling, experimental analysis, and artificial intelligence algorithms to analyze complex acoustofluidic phenomena. The researchers included an innovative use of dualized pressure acoustic fields and strategically located them at critical channel geometry positions on a lithium niobate substrate. By means of acoustic pressure applied within the microchannel, the system design provides for the generation of reliable datasets.

New research has identified a unique genetic signature in bacteria that can predict their likelihood of developing antibiotic resistance, a finding that can help quickly identify precision-based treatments that are more effective against the deadly, treatment-resistant pathogens.

Mitochondria organelles came from primordial bacterial endosymbionts and still preserve distinct genes for important functions like making ATP. To speed the emerging therapeutic research into the transfer of mitochondria between cells, 31 researchers have developed consensus recommendations for common terminology that describes mitochondria transfer and transplantation.

A person's lifetime risk for cancer may begin before they are even born, reports a paradigm-shifting study. The findings identified two distinct epigenetic states that arise during development and are linked to cancer risk. One of these states is associated with a lower lifetime risk while the other is associated with a higher lifetime risk.

Basal cell carcinomas, the most common form of skin cancer, occur in chronically sun-exposed areas such as the face. Locally advanced tumors in particular can be difficult to treat surgically. A research team has now investigated the effectiveness of a new type of therapy and achieved promising results: The active substance TVEC led to a reduction in the size of the basal cell carcinoma in all study participants, which not only improved surgical removal, but also led to a complete regression of the tumor in some of the patients.

Statins, a class of cholesterol-lowering drugs, have no effect on kidney function, a research team has found.

Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefited from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy regimen, according to results from the PhaseIII BREAKWATER trial.

Scientists have developed a groundbreaking approach using specially designed peptides to improve drug formulations. This innovative method significantly enhances anti-tumor efficacy.

A research team made a pivotal discovery in the field of cancer immunotherapy. The team identified a specific population of immune cells that play a critical role in successful treatment of relapsed acute myeloid leukemia (AML).

A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical lesions, according to the results from a phase II clinical trial.